Deletion by MLPA: BRCA1 and BRCA2
What's included in the price
- MLPA analysis — detection of large deletions and duplications
- In-house result interpretation by our own team
- Material collection / delivery per instructions
- Result available online in the patient portal (PDF)
A consultation with a clinical geneticist is available as a separate service. See the clinic
About this test
The BRCA1 and BRCA2 genes play a key role in the repair of DNA damage. Inherited pathogenic variants of these genes significantly increase the risk of breast and ovarian cancer, as well as pancreatic and prostate cancer (autosomal dominant inheritance).
Some changes in the BRCA1 and BRCA2 genes are large deletions or duplications spanning whole exons, which are not detected by standard NGS sequencing. In this test we use MLPA technology to examine both genes for such large deletions and duplications — as a complement to NGS analysis.
Genes analysed (2)
| Gene | Inheritance | Associated condition |
|---|---|---|
| BRCA1 | autosomal dominant | Breast cancer, Breast-Ovarian cancer, familial, susceptibility to, 1, Li-Fraumeni syndrome 2, Noonan syndrome 7 |
| BRCA2 | AD/AR | Breast cancer, Breast-Ovarian cancer, familial, susceptibility to, 1, Breast-Ovarian cancer, familial, susceptibility to, 2, Glioma susceptibility 3, Glioma susceptibility 3, Pancreatic cancer, susceptibility to, 2, Wilms tumor 1 |
Click a gene to see a single-gene test.
How the test works
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1
Order online
No referral needed. You order online.
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2
Collect the sample
Sample: Venous blood or DNA.
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3
Result
Available in 26 working days from sample registration in laboratory, online.
Frequently asked questions
How long does the Deletion by MLPA: BRCA1 and BRCA2 test take?
The result is usually available within 26 working days from sample registration in laboratory.
Do I need a referral?
No. You can order this genetic test online without a referral.
How many genes does this panel cover?
The panel analyses 2 genes.
How much does the test cost?
The price of the test is 445 EUR.
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Ready to order Deletion by MLPA: BRCA1 and BRCA2
Order online — no referral needed.